Enicostemma littorale Blume- Scientific Monograph
Ayurvedic Name: Nahi, Maja-makka booti.
Habitat: It is found
Botany: E. littorale is a perennial herb attaining height of 5-20 inches. It produces yellow or white coloured flowers, which are arranged in clusters.
Chemistry: Bitter principle (swertimarine), two alkaloids (one gentianine and other‘s name not confirmed), ophelic acid and tannins.
In a study, Maroo and workers have shown hypoglycemic and antioxidant activity of methanol extract of E. littorale Blume. Administration of methanol extracts (2.5 g/kg body weight/day) to diabetic rats for 20 days reduced blood glucose levels from 466.50+ 37.07 to 237.20+ 28.22. The extract not only raised the serum insulin levels but improved the antioxidant status of the rats also.
In another study, Maroo and workers studied the dose dependent blood glucose lowering effect of aqueous extract of E. littorale Blume in alloxan diabetic rats. 1.5 G dry plant caused significant decrease in glycosylated hemoglobin, liver glucose-6-phosphataseactivity and significant increase in serum insulin levels of the diabetic rat.